The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cells
Recent studies have shown that certain speci c microbial infections participate in atherosclerosis by inducing in ammation and immune reactions, but how the pathogens implicated in this pathology trigger the host responses remains unknown. In this study we show that Helicobacter cinaedi (Hc) is a human pathogen linked to atherosclerosis development since at least 27% of sera from atherosclerotic patients speci cally recognize a protein of the Hc proteome, that we named Cinaedi Atherosclerosis In ammatory Protein (CAIP) (n = 71).