Ricerc@Sapienza

The hepatitis B virus (HBV) infection represents
a global health problem; it can be transmitted through contact
with infected blood or other body fluids and it is dangerous
being highly contagious. Hepatitis B is preventable with effective
vaccine, as it is strongly recommended by the World
Health Organization; its protection is possibly life-long, at least
20 years. Mathematical modelling is a useful tool to study the
evolution of an epidemic spread and possibly to suggest suitable

The gut microbiota is now considered as a symbiotic organ playing an important role in human health and disease
development and has been recently recognized as a modulator of drug metabolism and toxicity. Here, we briefly
discuss new findings describing how the gut microbiota is now considered to be a central player in drug metabolism
and personalized medicine.