Left-sided early onset colorectal carcinomas: a sporadic neoplasm with aggressive behavior
BACKGROUND:
Early onset (?50y) colorectal carcinomas (EO-CRCs) are increasing in incidence according to epidemiological data. We investigated clinical-pathological, molecular features and outcomes of 62 left sided EO-CRCs (EOLS-CRCs) and compared them to a group of late onset (?65) LS-CRCs (LOLS-CRCs).
MATERIALS AND METHODS:
Samples were evaluated for pathological features and microsatellite instability (MSI). Overall survival (OS), disease free survival (DFS) and disease specific survival were evaluated in both groups.
RESULTS: