Ricerc@Sapienza

Introduction: The factor VIII (FVIII)-mimetic bispecific monoclonal antibody, emicizumab, previously approved for prophylaxis in haemophilia A with inhibitors, has been recently licensed in several countries also in patients with severe haemophilia A (PWSHA) without inhibitors.

The contribution reports the data related to the monitoring of the first year of the project "Solo posti in piedi. Educare oltre i banchi", financed by the Social Enterprise “Con i Bambini”, with the aim of fighting educational poverty in L'Aquila, ten years after the earthquake that struck it in 2009. The monitoring action was carried out by the University of L'Aquila through the administration of questionnaires to students, parents and teachers involved in the project actions.

While the new virus spreads worldwide and vaccines are yet to come, transport policy makers face a dilemma: how mobility is going to change? The situation is not unprecedented. But, unlike in past times when medical science was at early stages and little technology was available, counteractions currently undertaken by national and supranational governments integrate highest medical knowledge and technological skills with new, fast-adaptive lifestyles and transport patterns.

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal neoplasms (85%) of the gastrointestinal (GI) tract; duodenal GISTs constitute 3-5% of all GISTs and represent 10-30% of all malignant tumours of the duodenum. Rarely, patients present severe bowel obstruction, perforation or severe bleeding. The radical resection with complete removal of the tumour remains the main therapeutic approach. We performed a local resection in patients with suspected GIST admitted for emergency treatment for GI bleeding.

Aim: To investigate whether differences in histotype in colon cancer correlate with clinical presentation and if they might influence oncological outcomes and survival. Methods: Data regarding colon cancer patients operated both electively or in emergency between 2009 and 2014 were retrospectively collected from a prospectively maintained database and analyzed for the purpose of this study. Rectal cancer was excluded from this analysis.