Ricerc@Sapienza

The ageing of the world population has resulted in an increase in the number of older patients with multimorbid conditions receiving multiple therapies. This emerging clinical scenario poses new challenges, which are mostly related to the increased incidence of adverse effects. This translates into poor clinical care, reduced cost-effectiveness of drug therapies, and social isolation of multimorbid patients due to reduced autonomy.

Accumulation of oxidative insults on molecular and supramolecular levels could compromise renewal potency and architecture in the aging skin.

Background: A convenient approach to modulation of the inflammation has an influence on the production of inflammatory mediators – icosanoids, generated in arachidonic acid (AA) metabolism. The common therapeutic activity of non-steroidal anti-inflammatory drugs (NSAID), such as aspirin, includes inhibition of two crucial enzymes of AA metabolism-cyclooxygenase-1 and-2 (COX-1/2), with certain risk for gastrointestinal and renal intolerance.

Throughout the world, the fossil fuel has supplied around the 80% of the energetic requirements, in Colombia alone 95.1% of energetic demand is made by the transportation sector solely, supplied by oil, kerosene, gasoline and diesel, this sector has an extremely small participation with biofuel of 3%, which is represented only by biodiesel. Microalgae had been proposed as biofactories with a remarkable third generation biofuels production.

This work investigates the morphology, the thermal, and
mechanical properties of technical fibers extracted from
the Ampelodesmos mauritanicus (Diss) grass using a process
that combines mechanical, mild chemical, and enzymatic
steps. The structure and the thermal stability of Diss
fibers make them suitable as a reinforcing filler in polymer
composites, which was assessed by manufacturing biocomposites
with improved stiffness and a tensile strength
not degraded by Diss fibers when compared to those of a

In this study, polythiophene copolymers have been used as modifier for electrode surfaces in order to allow the immobilization of active pyrroloquinoline quinone dependent glucose dehydrogenase (PQQ-GDH) and to simultaneously improve the direct electrical connection of the enzyme with the electrode. Polymer films are electrosynthesized in aqueous solution without the need of surfactants onto carbon nanotubes modified gold electrodes from mixtures of 3-thiopheneacetic acid (ThCH2CO2H) and 3-methoxythiophene (ThOCH3) using a potentiostatic pulse method.

Among the emerging issues in the field of wastewater treatments, reducing energy
consumption and removal of new organic pollutants have become of primary concern.
With respect to the first goal, alternating oxic/anoxic conditions in the bioreactor
has demonstrated to be a feasible way to ensure the required efficiency of carbon
and nitrogen removal along with energy saving. The aim of the present study was
to investigate if these alternating oxic/anoxic conditions are also capable of boosting