Menopausal symptoms: from soy isoflavones to combined soy-exercise interventions
Diet and physical activity affect menopausal symptoms. We aimed to review recent evidence based on clinical trials and meta-analysis on the effect of soy isoflavones on menopausal symptoms and the potential synergistic effect of soy consumption and exercise on menopausal women. Many studies have investigated the effect of soy isoflavones on menopausal symptoms and the data indicates that equol status is the main determinant for efficacy. Despite this, it is well known that exercise changes microbiota composition.