Ricerc@Sapienza

The alkali-activation of titanium (Ti) surfaces performed in a heated sodium hydroxide (NaOH) aqueous solution, results in a porous layer rich in hydroxyl (OH) groups, the structure and porosity of which strongly depend on the reaction time and NaOH concentration used.

The benzoin condensation starting from benzaldehyde and the subsequent benzoin amidation to benzamide can be efficiently carried out under very mild conditions in an electrolysis cell. Among the advantages of using electrochemistry to generate our active reagents, the use of the easily dosed and non pollutant electron, instead of stoichiometric amounts of redox reagents or bases, usually renders the electrochemical methodology “greener” than classical organic reactions. Benzoin is obtained in good yield (85 %) carrying out the reaction in the room temperature ionic liquid BMIm-BF4.

Pure Appl. Chem. 2019; 91(10): 1549–1552 Preface Luciana Dini*, Daniele Passeri, Cristian Vergallo and Marco Rossi 15th Eurasia Conference on Chemical Sciences (EuAsC2S-15) – 5th–8th September 2018, Rome, Italy https://doi.org/10.1515/pac-2019-0904 Keywords: 15th Eurasia Conference on Chemical Sciences; EuAsC2S-15; Eurasia 2018. Around 1985–1986, Prof. Bernd M. Rode from the University of Innsbruck (Austria) suggested with Prof.

The bystander effect (BE) is an important biological phenomenon that induces damages in distant and not directly affected by a chemical/physical stress cells. This effect, well known in ionizing radiation treatment, relies on reactive signals released by exposed cells and transmitted via cell–cell interaction or culture medium. In this study, cycloheximide (CHX)-induced apoptotic U937 cells and untreated THP-1 cells were chosen to investigate the chemical-induced BE.

Azadirachta indica (neem) is a tropical and semi-tropical tree native to the whole Indian subcontinent. Neem leaves are rich in flavonoids, which exhibit important pharmacological activities targeting almost all human organs. In order to produce a purified extract of neem leaves enriched of antioxidant and antidiabetic flavonoids, the ethanolic extract of neem leaves has been further undergone to liquid-liquid extractions by using three different organic solvents, i.e. dichloromethane, n-butanol and ethyl acetate.

In this work we used a combination of different techniques to investigate the adsorption properties of curcumin by zeolite type A for potential use as an anticancer drug carrier. Curcumin is a natural water-insoluble drug that has attracted great attention in recent years due to its potential anticancer effect in suppressing many types of cancers, while showing a synergistic antitumor effect with other anticancer agents. However, curcumin is poorly soluble in aqueous solutions leading to the application of high drug dosage in oral formulations.