Ricerc@Sapienza

Imbalance of the iron level in the body causes several diseases. In particular, the low level of iron, during pregnancy, is
responsible for the iron deficiency anemia, and even of neurodegenerative diseases. Although the treatment of iron
deficiency anemia with oral iron supplements has been known, this problem still afflicts many people. The aim of this work
was the development of a system able to release ferrous ions in a controlled manner. Controlled drug release for medical

The aim of this work is the development of a system able to release ferrous
ions in a controlled manner. An interesting alternative to a systemic therapy
can be the use of controlled drug release for medical applications. Starting
from iron powder and citric acid, ferrous citrate (Fe(II)C) is synthesized by a
redox reaction between these two. The confirmation that only Fe(II)C is
obtained by redox reaction is shown from Fourier transform infrared
spectroscopy (FTIR), 1,10-phenanthroline and sodium thiocyanate