fission

The role of mitochondrial dynamics in cardiovascular diseases

The process of mitochondrial dynamics is emerging as a core player in cardiovascular homeostasis. This process refers to the co-ordinated cycles of biogenesis, fusion, fission and degradation to which mitochondria constantly undergo to maintain their integrity, distribution and size. These mechanisms represent an early response to mitochondrial stress, confining organelle portions that are irreversibly damaged and preserving mitochondrial function.

Numerical analysis of temperature stratification in the CIRCE pool facility

In the framework of Heavy Liquid Metal (HLM) GEN IV Nuclear reactor development, the focus is in the combination of security and performance. Numerical simulations with Computational Fluid Dynamics (CFD) or system codes are useful tools to predict the main steady-state phenomena and how transitional accidents could unfold in GEN IV reactors. In this paper, to support the validation of CFD as a valid tool for the design, the capability of ANSYS CFX v15.0 to simulate and reproduce mixed natural convection and thermal stratification phenomena inside a pool is investigated.

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma