gastric cytopathology

Preoperative gastric lavage in gastric cancer patients undergoing surgical, endoscopic or minimally invasive treatment: an oncological measure preventing peritoneal spillage of intragastric cancer cells and development of related metastases

In addition to classical metastatic pathways, recently gastric cancer was described having an alternative route
called “endoluminal exfoliation”. Provisional analyses demonstrated, in fact, this kind of shedding is associated
with several clinico-pathological features indicative of aggressive behavior and resulted to be an independent
prognostic factor entailing poor prognosis. Compared with non-sowing counterparts, in fact, patients affected
with exfoliating early and advanced gastric carcinomas met with shorter overall survival, disease free survival,

Presence of cancer cells in gastric lavage of gastric cancer patients as an indicator of advanced disease, predictor of tumour aggressive phenotype and independent prognostic factor for poor survival: the endoluminal pathway of gastric cancer and GL0

OBJECTIVE:
As of 2017, the pathobiology of gastric cancer (GC) is far from fully understood; consequently, new methods of basic and advanced research have been proposed and tested. The presence (GL1) vs absence (GL0) of malignant cells exfoliated in gastric lavage (GL) of GC patients was formerly evaluated with diagnostic intent but not for staging or prognostic assessment. We investigated this hitherto unreported application of cytopathology.

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