Efficacy of gelatin tannate for acute diarrhea in children: A systematic review and meta-analysis
Aim: To investigate by meta-analysis the efficacy of gelatin tannate (GT), a mucosal barrier protector, in children with acute gastroenteritis. Methods: A comprehensive literature search was conducted. Studies were selected according to PICO: Participants: children aged 0-12 years with acute diarrhea; Intervention: GT; Comparison: oral rehydration solution and/or placebo; Outcomes: diarrhea-related outcomes. Results: Three published randomized controlled trials were identified of pediatric diarrhea treated with GT (n = 203) or control (n = 204).