genetics and molecular biology

Ancient DNA analysis of dental calculus to infer lifestyle, health and origin of human populations

Ancient DNA analysis of dental calculus to infer lifestyle, health and origin of human populations

With Katerina Guschanski (University of Edinburgh) and Mary Anne Tafuri (Sapienza University) we are using ancient DNA extracted from dental calculus of classical and post-classical individuals dating to I-VIII century CE, to gain novel insights into the diets, health statuses, and origins of human populations that lived in central Italy.

Lean body weight-tailored Iodinated contrast Injection in obese patient. boer versus James Formula

Purpose. To prospectively compare the performance of James and Boer formula in contrast media (CM) administration, in terms of image quality and parenchymal enhancement in obese patients undergoing CT of the abdomen. Materials and Methods. Fifty-five patients with a body mass index (BMI) greater than 35 kg/m2were prospectively included in the study. All patients underwent 64-row CT examination and were randomly divided in two groups: 26 patients in Group A and 29 patients in Group B.

Collaboration between a human group and artificial intelligence can improve prediction of multiple sclerosis course. A proof-of-principle study

Background: Multiple sclerosis has an extremely variable natural course. In most patients, disease starts with a relapsing-remitting (RR) phase, which proceeds to a secondary progressive (SP) form. The duration of the RR phase is hard to predict, and to date predictions on the rate of disease progression remain suboptimal. This limits the opportunity to tailor therapy on an individual patient's prognosis, in spite of the choice of several therapeutic options.

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