Health
Careful with that axe, gene, genome perturbation after a PEG-mediated protoplast transformation in Fusarium verticillioides
Phenomenological configurations of workplace bullying. A cluster approach
The present study represents an innovative contribution combining an articulated description of phenomenological manifestations of bullying with an in-depth picture of individual processes operating within the regulative system. Phenomenological con figurations of bullying were identi fied considering not only exposure to and types of bullying, but also two of its main correlates: health problems and deviant behaviour.
A Multi-stakeholder Framework to Facilitate Policy Making in the Use of BES Data: A Focus on Health in South Tyrol
We present a statistical analysis aimed at investigating the quality of the health domain of BES in South Tyrol. After having summarized the academic debate on the distinction between objective and subjective indicators and on the use of subjective measures in policy making, we illustrate the rationale behind the approach adopted to interpret the available data. We observe how the heterogeneity of the stakeholders influences the way in which information is turned into policy action and the conflicts of interests that might arise must be resolved.
Spending on health and HIV/AIDS: domestic health spending and development assistance in 188 countries, 1995–2015
Comparable estimates of health spending are crucial for the assessment of health systems and to
optimally deploy health resources. The methods used to track health spending continue to evolve, but little is known
about the distribution of spending across diseases. We developed improved estimates of health spending by source,
including development assistance for health, and, for the first time, estimated HIV/AIDS spending on prevention and
treatment and by source of funding, for 188 countries.
Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps
Several ATP-binding cassette (ABC) proteins reduce intracellular concentrations of antitumor drugs and hence weaken the response of cancer cells to chemotherapy. Accordingly, the inhibition of these export pumps constitutes a promising strategy to chemosensitize highly chemoresistant tumors, such as hepatocellular carcinoma (HCC). Here, we have investigated the ability of β-caryophyllene oxide (CRYO), a naturally occurring sesquiterpene component of many essential oils, to inhibit, at non-toxic doses, ABC pumps and improve the response of HCC cells to sorafenib.
Arsenic-contaminated freshwater: assessing arsenate and arsenite toxicity and low-dose genotoxicity in Gammarus elvirae (Crustacea; Amphipoda)
Arsenic (As) contamination of freshwater is largely due to geogenic processes, but As is also released into the environment because of improper anthropic activities. The European regulatory limits in drinking water are of 10?gL?1 As. However, knowledge of the genotoxic effects induced by low doses of As in freshwater environments is still scanty. This study was designed to investigate arsenate (As(V)) and arsenite (As(III)) toxicity and low-dose genotoxicity in Gammarus elvirae, which has proved to be a useful organism for genotoxicity assays in freshwater.
Exposure to residential greenness as a predictor of cause-specific mortality and stroke incidence in the Rome longitudinal study
BACKGROUND: Living in areas with higher levels of surrounding greenness and access to urban green areas have been associated with beneficial health outcomes. Some studies suggested a beneficial influence on mortality, but the evidence is still controversial. OBJECTIVES: We used longitudinal data from a large cohort to estimate associations of two measures of residential greenness exposure with cause-specific mortality and stroke incidence. METHODS: We studied a population-based cohort of 1,263,721 residents in Rome aged [Formula: see text], followed from 2001 to 2013.
Veleni e antidoti. Contraddizioni sul tema dell’evironmentalism nella cultura urbana americana contemporanea
È difficile trovare un saggio pubblicato negli ultimi cinque anni che tratti di politiche urbane, di welfare e di città che non contenga un riferimento, ancorché sommario, al tema “città e salute” e alla sua attuale interpretazione nei contesti accademici o nelle agende politiche. Ciò è particolarmente evidente nei lavori che si occupano degli Stati Uniti d’America, dove i temi dell’environmentalism, analizzati in dossier e studi, hanno una tradizione di lungo corso, non priva di contraddizioni 1.
Definition and diagnostic criteria for orthorexia nervosa: a narrative review of the literature
In some cases, detrimental consequences on health are generated by self-imposed dietary rules intended to promote health. The pursuit of an "extreme dietary purity" due to an exaggerated focus on food may lead to a disordered eating behavior called "orthorexia nervosa" (ON). ON raises a growing interest, but at present there is no universally shared definition of ON, the diagnostic criteria are under debate, and the psychometric instruments used in the literature revealed some flaws.