Anti-HLA donor-specific antibodies in allogeneic stem cell transplantation: management and desensitization protocol
The role of antibodies directed against the human leukocyte antigen (HLA) system has been well analyzed in rejection of solid organ transplantations [1, 2] and in transfusion medicine [3]. In the setting of allogeneic hematopoietic stem cells transplantation (HSCT), only in the recent years their importance has been better defined, even though antiHLA antibodies are frequently detectable in hematologic