Ricerc@Sapienza

Energy-based methodology is utilized to design novel timber-steel hybrid core wall system. The timber-steel core wall system consists of cross laminated timber (CLT), steel columns, angled brackets and t-stub connections. The CLT wall panels are stiff and strong, and ductility is provided through the steel t-stub connections. The structural system was modelled in SAP2000 finite element program. The hybrid system is explained in detail and validated using first principles.

In-Silico Clinical Trials (ISCT), i.e., clinical experimental campaigns carried out by means of computer simulations, hold the promise to decrease time and cost for the safety and efficacy assessment of pharmacological treatments, reduce the need for animal and human testing, and enable precision medicine.

The proposed analysis is focused on the project and the technical and economical evaluation of a ground source heat pump system for heating and cooling an industrial building. The project of the plant consists of two phases: the design of the heating and cooling system and the design of the geothermal probes field. The optimization of the system has been the target of the entire design process. The proposed solution is an hybrid system: two ground source heat pumps, coupled with a back-up condensing boiler.