IL-4 | Ricerc@Sapienza

Clinical and immunological effects of a treatment with desentizating low-dose multicomponents in IgE mediated and non IgE mediated food allergies: observational retrospective pilot study

Background. Alimentary allergy has high impact on the quality of life (Qol) of patients and their families: it represents an economic
burden for individuals and National Health System. The disease, particularly frequent in pediatric age, recognizes different pathogenetic

Role of invariant natural killer t cells in patients with tonsillar hypertrophy: the tonsil as an immunological organ

Radiation increases functional KCa3.1 expression and invasiveness in glioblastoma

Glioblastoma (GBM) is a deadly brain tumor, with fast recurrence even after surgical intervention, radio- and chemotherapies. One of the reasons for relapse is the early invasion of surrounding brain parenchyma by GBM, rendering tumor eradication difficult. Recent studies demonstrate that, in addition to eliminate possible residual tumoral cells after surgery, radiation stimulates the infiltrative behavior of GBM cells. The intermediate conductance of Ca2+-activated potassium channels (KCa3.1) play an important role in regulating the migration of GBM.