intensive care unit | Ricerc@Sapienza

Therapeutic Hypothermia in Critically Ill Patients: A Systematic Review and Meta-Analysis of High Quality Randomized Trials

Objectives: To investigate the effect of the application of therapeutic hypothermia (32-35°C) on survival and major clinical endpoints in critically ill patients. Data Sources: We searched online database and clinical trial registries dated up to April 30, 2019, and references of relevant studies. Study Selection: Low risk of bias randomized trials which compared hypothermia applied for at least 24 hours and conventional therapy in critically ill patients were included.

Prevention of medication errors during intravenous drug administration in intensive care units. a literature review

Medication errors during drug administration represent a current issue in intensive care units due to the complexity of patients, the large quantity of drugs administered intravenously, the frequent prescription changes and frenetic activities in an emergency setting. The aim of this review is to increase knowledge about prevention and types of medication errors in intensive care units. The review was conducted using the following biomedical databases:

Instruments to facilitate the decision-making process on how to administer infusions simultaneously in intensive care units. An Italian experience [Strumenti per facilitare il processo decisionale sulla modalità di somministrazione di infusioni in c

Riassunto. Introduzione. Nessun setting assistenziale è scevro da errori da terapia farmacologica. Diversi studi mostrano tuttavia percentuali maggiori in Terapia Intensiva, ove l’intensità clinica e la complessità assistenziale della persona ricoverata sono particolarmente elevate. Il paziente ricoverato in un setting di alta intensità è una persona critica, che generalmente assume una maggiore quantità di farmaci, prevalentemente per via endovenosa.

Impact of continuous renal replacement therapy (CRRT) and other extracorporeal support techniques on procalcitonin guided antibiotic therapy in critically ill patients with septic shock

Antimicrobial stewardship program, COVID-19, and Infection control. Spread of carbapenem-resistant klebsiella pneumoniae colonization in ICU COVID-19 patients. What did not work ?

The Italian burden of disease associated with infections due to antibiotic-resistant bacteria has been very high, largely attributed to Carbapenem-Resistant Klebsiella pneumoniae (CR-Kp). The implementation of infection control measures and antimicrobial stewardship programs (ASP) has been shown to reduce healthcare-related infections caused by multidrug resistance (MDR) germs. Since 2016, in our teaching hospital of Terni, an ASP has been implemented in an intensive care unit (ICU) setting, with the “daily-ICU round strategy” and particular attention to infection control measures.

Multimodal surveillance of healthcare associated infections in an intensive care unit of a large teaching hospital

BACKGROUND:
Healthcare-associated infections (HAIs), or nosocomial infections, represent a significant burden in terms of mortality, morbidity, length of stay and costs for patients hospitalized in intensive care units (ICUs). Surveillance systems are recommended by national and international institutions to gather data on HAIs in order to develop and evaluate interventions that reduce the risk of HAIs.