Ricerc@Sapienza

Purpose: To validate a novel consensus method, called target-in-target, combining human analysis of mpMRI with automated CAD system analysis, with the aim to increasing the prostate cancer detection rate of targeted biopsies. Methods: A cohort of 420 patients was enrolled and 253 patients were rolled out, due to exclusion criteria. 167 patients, underwent diagnostic 3T MpMRI. Two expert radiologists evaluated the exams adopting PI-RADSv2 and CAD system. When a CAD target overlapped with a radiologic one, we performed the biopsy in the overlapping area which we defined as target-in-target.

Purpose of Review Placenta accreta spectrum disorders encompass a heterogeneous group of conditions classified according to the degree of invasion of the trophoblastic tissue trough the myometrium and uterine serosa with a detrimental effect on maternal outcomes, including life-threatening hemorrhage, need for blood transfusion, damage to adjacent organs, and eventually death, and this highlights the need of additional procedures to improve surgery.