Ricerc@Sapienza

This paper presents the development of a lab-on-chip, based on thin-film sensors, suitable for DNA treatments. In particular, the system performs on-chip DNA amplification and separation of double-strand DNA into single-strand DNA, combining a polydimethylsiloxane microfluidic network, thin-film electronic devices, and surface chemistry.

This article investigates the stability of hydrogenated amorphous silicon (a-Si:H) p-i-n junctions employed as temperature sensors in lab-on-chip (LoC) applications. The devices have been tested under forward current injection and different temperatures (from room temperature up to 90 °C) in order to reproduce the practical operating conditions. Two sets of devices with different diborane concentrations in the p-doped layer have been investigated as a case study.