liver metastasis | Ricerc@Sapienza

CT texture analysis of liver metastases in PNETs versus NPNETs: correlation with histopathological findings

Purpose: To compare CT and Texture features of liver metastases in Pancreatic Neuroendocrine Tumors (PNETs) and in Non-Pancreatic Neuroendocrine Tumors (NPNETs) according to tumor grading, overall survival (OS), time to progression (TTP) and Ki67 index. Methods: 23 patients with PNETs and 25 patients with NPNETs affected by liver metastases were compared. The lesions were G1 and G2 according to WHO classification of tumors.

Tumor regression grades, K-RAS mutational profile and c-MET in colorectal liver metastases

Recently TRG, necrosis grade and the rate of viable cancer cells of colorectal liver metastases were correlated with the response to chemotherapy treatments, whereas K-RAS mutations and c-MET over-expression were correlated with the prognosis.