Camellia sinensis in asymptomatic hyperuricaemia: a meta-analysis of tea or tea extract effects on uric acid levels
Flavanols of Camellia sinensis exhibit uric acid (UA) lowering effect, through the modulation of both xanthine oxidase and urate excretion. In order to investigate the potential benefit of Camellia Sinenis products in asymptomatic hyperuricaemia, a meta-analysis of long-term Randomized Controlled Trials (RCT) with tea or tea extract has been conducted. From 20 human intervention studies selected only 5 RCT (13 interventions) were suitable for meta-analysis (n=472). The current "normal" range set for hyperuricaemia fails to identify patients with potential metabolic disorders.