Ricerc@Sapienza

The rapid development and adoption of Internet and digital technologies
dramatically changed business processes, leading to a disruptive digital transformation
of the whole industry value chain. The so-called Industry 4.0 refers to a
complex evolution of the entire industrial sector that includes technological
advances in production equipment (i.e. Additive Manufacturing), smart finished
products (IoT), data tools and analytics, involving activities and stakeholders at all

In recent years, the publication of the studies on the transmissibility in mammals of the H5N1 influenza virus and synthetic genomes has triggered heated and concerned debate within the community of scientists on biological dual-use research; these papers have raised the awareness that, in some cases, fundamental research could be directed to harmful experiments, with the purpose of developing a weapon that could be used by a bioterrorist.

This paper aims at being a comprehensive reference for stakeholders, policy makers, and scholars interested in analyzing the problem of efficiency, effectiveness, and impacts of rail transport systems in a sound empirical way, paying specific attention to passenger transport services. The paper combines different analytical frameworks (engineering, economics, impacts), systematic review techniques, and advanced mappings. Framing economic efficiency studies into a transport planning perspective permits to move from efficiency to effectiveness issues.