Multivariate data analysis | Ricerc@Sapienza

NMR-based metabolomics approach to study urines of chronic inflammatory rheumatic diseases patients.

The nuclear magnetic resonance (NMR)-based
metabolomic approach was used as analytical methodology
to study the urine samples of chronic inflammatory rheumatic
disease (CIRD) patients. The urine samples of CIRD patients
were compared to the ones of both healthy subjects and pa-
tients with multiple sclerosis (MS), another immuno-mediated
disease. Urine samples collected from 39 CIRD patients, 25
healthy subjects, and 26 MS patients were analyzed using
1
H
NMR spectroscopy, and the NMR spectra were examined

A multivariate statistical approach for the estimation of the ethnic origin of unknown genetic profiles in forensic genetics

DNA typing and genetic profile data interpretation are among the most relevant topics in forensic science; among other applications, genetic profile’s capability to distinguish biogeographic information about population groups, subgroups and affiliations have been largely explored in the last decade. In fact, for investigative and intelligence purposes, it is extremely useful to identify subjects and estimate their biogeographic origins by examining the recovered DNA profiles from evidence on a crime scene.