nanomaterials

Nanomaterial-based sensors for a real-time detection of radiation damage in space environment

In this work, the fabrication and properties of ultraviolet-sensing films based on hybrid nanomaterials, containing graphene nanoplatelets (GNP) as signal transducer and DNA as UV-sensitive element, are investigated. The sensor components are prepared by sonication-driven non-covalent assembly and are embedded in a polymer matrix for enhanced adhesion on several types of space-grade materials and structures. We show that these nanomaterial sensing films can be used to monitor the effects of UV radiation exposure in real time.

Molecular mechanisms and new therapeutic targets in epithelial to mesenchymal transition (EMT) and fibrosis

Although the term “epithelial to mesenchymal transformation” was used for the first time by Betty Hay in 1968, the earliest description of the EMT process probably dates back to drawings made by the Nobel Prize Santiago Ramòn y Cajal around 1890 (López-Novoa and Nieto, 2009).

Impact of the protein corona on nanomaterial immune response and targeting ability

Over the last decade nanomaterials have had a major impact on human health for the early detection and treatment of many diseases. The future success of clinically translatable nanomaterials lies in the combination of several functionalities to realize a personalized medical experience for patients. To maintain promises, concerns arising from toxic potential and off-target accumulation of nanomaterials must be addressed first.

© Università degli Studi di Roma "La Sapienza" - Piazzale Aldo Moro 5, 00185 Roma