Early markers of angiogenesis and ischemia during bowel conduit neovascularization
Background?Bowel flaps are a good and reliable method to restore the continuity of the aerodigestive tract. Radiated fields, contaminated recipient sites, or depleted recipient vessels may increase the risk for ischemic injury after transfer. During ischemic events, we believe that bowel conduits with serosa have a delayed neovascularization process at its new recipient site.
We conducted an ischemia/reperfusion murine model to understand the difference among bowel conduits with and without serosa.