non-steroidal anti-inflammatory drugs

Effects of ibuprofen administration timing on oral surgery pain: a randomized clinical trial

Objective This study aimed to compare the analgesic effect of ibuprofen 400 mg given 30 minutes before or immediately after third molars surgery under local anaesthesia. Materials and Methods The single‐center, randomized, split‐mouth, triple‐blind, clinical trial involved 38 outpatients, for a total of 76 bilateral symmetrical fully bone impacted mandibular third molars. Each patient was undergone to separate surgical sessions for the right and left side, and ibuprofen was randomly administered 30 minutes before or immediately after the intervention.

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

BACKGROUND: Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery. METHODS: A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included.

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