Ricerc@Sapienza

Objectives: To update the 2012 ESGAR consensus guidelines on the acquisition, interpretation and reporting of magnetic resonance imaging (MRI) for clinical staging and restaging of rectal cancer. Methods Fourteen abdominal imaging experts from the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) participated in a consensus meeting, organised according to an adaptation of the RAND-UCLA Appropriateness Method. Two independent (non-voting) Chairs facilitated the meeting.

Purpose: The purpose of this study was to assess the impact of adaptive statistical iterative reconstruction (ASiR) on half-dose coronary artery calcium scoring (CACS) acquisition protocol. Materials and Methods: Between September 2016 and October 2017, 89 patients (54 male patients, mean age 64.6±10.7?y) with a clinically indicated coronary computed tomography angiography were prospectively enrolled.

BACKGROUND:
Reconstruction options following nipple-sparing mastectomy (NSM) are diverse and not yet investigated with level IA evidence. The analysis of surgical and oncological outcomes of NSM from the Italian National Registry shows its safety and wide acceptance both for prophylactic and therapeutic cases. A further in-depth analysis of the reconstructive approaches with their trend over time and their failures is the aim of this study.
METHODS:

Charged particle beams are used in particle therapy (PT) to treat oncological patients due to their selective dose deposition in tissues with respect to the photons and electrons used in conventional radiotherapy. Heavy (Z > 1) PT beams can additionally be exploited for their high biological effectiveness in killing cancer cells. Nowadays, protons and carbon ions are used in PT clinical routines. Recently, interest in the potential application of helium and oxygen beams has been growing.

Nowadays there is a growing interest in particle therapy treatments exploiting
light ion beams against tumors due to their enhanced relative biological
effectiveness and high space selectivity. In particular promising results are
obtained by the use of 4He projectiles. Unlike the treatments performed
using protons, the beam ions can undergo a fragmentation process when
interacting with the atomic nuclei in the patient body. In this paper the results
of measurements performed at the Heidelberg Ion-Beam Therapy center are

Charged particle therapy is a technique for cancer treatment that exploits hadron beams, mostly protons
and carbon ions. A critical issue is the monitoring of the beam range so to check the correct dose deposition
to the tumor and surrounding tissues. The design of a new tracking device for beam range real-time
monitoring in pencil beam carbon ion therapy is presented. The proposed device tracks secondary
charged particles produced by beam interactions in the patient tissue and exploits the correlation of

Ion beam therapy is a rapidly growing technique for tumor radiation therapy. Ions allow for a high dose deposition in the tumor region, while sparing the surrounding healthy tissue. For this reason, the highest possible accuracy in the calculation of dose and its spatial distribution is required in treatment planning. On one hand, commonly used treatment planning software solutions adopt a simplified beam–body interaction model by remapping pre-calculated dose distributions into a 3D water-equivalent representation of the patient morphology.

In Particle Therapy, cancer treatments are performed using accelerated charged particles whose high irradiation precision and conformity permit to destroy the tumour while sparing the surrounding healthy tissues. Several secondary particles are produced during the treatments mainly photons, protons and neutrons. The reduced attenuation length of neutrons yields a secondary particle sample that is larger in number when compared to photons and charged particles.

Purpose: The real-time monitoring of the spread-out Bragg peak would allow the planned dose delivered during treatment to be directly verified, but this poses a major challenge in modern ion beam therapy. A possible method to achieve this goal is to exploit the production of secondary particles by the nuclear reactions of the beam with the patient and correlate their emission profile to the planned target volume position. In this study, we present both the production rate and energy spectra of the prompt-?

Tumour control is performed in particle therapy using particles and ions, whose high irradiation precision enhances the effectiveness of the treatment, while sparing the healthy tissue surrounding the target volume.
Dose range monitoring devices using photons and charged particles produced by the beam interacting with the patient’s body have already been proposed, but no attempt has been made yet to exploit the detection of the abundant neutron component.