nutrition and dietetics | Ricerc@Sapienza

The anorexigenic peptide neurotensin relates to insulin sensitivity in obese patients after BPD or RYGB metabolic surgery

Neurotensin is a peptide with effects on appetite and intestinal lipid absorption. Experimental data suggest a role in glucose homeostasis, while human data is missing. Here, 20 morbidly obese subjects either underwent biliopancreatic diversion with duodenal switch (BPD), or Roux-en-Y gastric bypass (RYGB) in a randomized fashion. Before and 1 year after surgery, anthropometric data, body composition, clinical biochemistry, insulin sensitivity by means of euglycemic hyperinsulinemic clamps (HEC) and fasting plasma proneurotensin 1–117 were analyzed.

Safety and efficacy of a new swallowable intragastric balloon not needing endoscopy: early italian experience

PURPOSE: The aim of this study was to evaluate the safety and efficacy of a new intragastric balloon (Elipse™ Balloon, Allurion Technologies, Natick, MA USA) not needing endoscopy.
MATERIALS AND METHODS: The balloon was swallowed under fluoroscopy in 38 consecutive patients (F/M 28/10, mean age 46.4 ± 10.6 years, mean weight 109.7 ± 21.9 kg, and mean body mass index (BMI) 38.6 ± 6.7 kg/m2). After 4 months, the balloon spontaneously emptied and it was excreted through the digestive tract without upper endoscopy.

Rare Cause of Small Bowel Ischemia During Pregnancy After Roux-en-Y Gastric Bypass

no abstract

Gastric bypass and synchronous cholecystectomy. a matter of numbers?

No abstract available

Laparoscopic Conversion of One Anastomosis Gastric Bypass to a Standard Roux-en-Y Gastric Bypass

Introduction: One anastomosis gastric bypass (OAGB) demonstrated results similar to traditional Roux-en-Y procedures [1–3], in terms of weight loss and resolution of obesity-related comorbidities. The main controversy regarding OAGB is the concern for an association between biliary alkaline gastritis and esophageal or gastric cancer raised by some studies [4]. Methods: We present the case of a 51-year-old woman with a BMI of 41 kg/m2 who underwent a laparoscopic OAGB in 2014. One year later, she consulted for recurrent heartburns.

Migration of an Endoscopic Double Pigtail Drain into the Abdominal Wall Placed as a Treatment of a Fistula Post Revisional Bariatric Surgery

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Predictive Value of C-Reactive Protein for Complications Post-Laparoscopic Roux-en-Y Gastric Bypass

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Double Perforation of Marginal Ulcers after One Anastomosis Gastric Bypass with a Biliary Peritonitis

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A Simple Technique of Gastric Pouch Resizing for Inadequate Weight Loss After Roux-en-Y Gastric Bypass

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Increased intake of energy-dense diet and negative energy balance in a mouse model of chronic psychosocial defeat

Purpose: Chronic exposure to stress may represent a risk factor for developing metabolic and eating disorders, mostly driven by the overconsumption of easily accessible energy-dense palatable food, although the mechanisms involved remain still unclear. In this study, we used an ethologically oriented murine model of chronic stress caused by chronic psychosocial defeat (CPD) to investigate the effects of unrestricted access to a palatable high fat diet (HFD) on food intake, body weight, energy homeostasis, and expression of different brain neuropeptides.