Ricerc@Sapienza

Meligethes (Odonthogethes) trapezithorax sp. n., M. (O.) tricuspidatus sp. n., and M. (O.) luteomaculatus sp. n. are described from Hubei Province, China, based on a series of recently collected specimens. The new species appear morphologically closely related to M. (O.) brassicogethoides Audisio, Sabatelli Jelínek, 2015 from Yunnan [M. (O.) trapezithorax sp. n.], M. (O.) occultus Audisio, Sabatelli Jelínek, 2015 from Yunnan [M. (O.) tricuspidatus sp. n.], as well as M. (O.) pallidoelytrorum Chen Kirejtshuk, 2013 from Sichuan and M.

Recent work has implicated the actin cytoskeleton in tissue size control and tumourigenesis, but how changes in actin dynamics contribute to hyperplastic growth is still unclear. Overexpression of Pico, the only Drosophila Mig-10/RIAM/Lamellipodin adapter protein family member, has been linked to tissue overgrowth via its effect on the myocardin-related transcription factor (Mrtf), an F-actin sensor capable of activating serum response factor (SRF). Transcriptional changes induced by acute Mrtf/SRF signalling have been largely linked to actin biosynthesis and cytoskeletal regulation.