Capillary methacrylate-based monoliths by grafting from/to ?-ray polymerization on a tentacle-type reactive surface for the liquid chromatographic separations of small molecules and intact proteins
Capillary methacrylate-based monoliths were prepared for the high performance liquid chromatography(HPLC) separation of both small molecules and large biomolecules. An efficient grafting from/to syntheticapproach was adopted introducing a network of activated sites in the inner wall surface using the newsilanization agent (N-trimethoxysilylpropyl)-polyethylenimine.