Risk factors of Parkinson’s disease: Simultaneous assessment, interactions and etiological subtypes
Objective: To perform a simultaneous evaluation of potential risk/protective factors of Parkinson’s
disease (PD) in order to identify independent risk/protective factors, assess interaction among
factors and determine whether identified risk factors predict etiological subtypes of PD.
Methods: We designed a large case-control study assessing 31 protective/risk factors of PD,
including environmental and lifestyle factors, comorbidities, and drugs. The study enrolled 694 PD