Ricerc@Sapienza

During the past three decades, due to the development of new technologies that allow faster and more accurate virological diagnoses, clinical virology laboratory has taken on an important role in the patient’s clinical management. Besides, it is now possible to define, more quickly and precisely than before, viral gene sequences related to specific viral variants (including drug-resistant strains) or to viral and host factors that can affect the natural history of infections.

Lab-on-Chip are miniaturized systems able to perform biomolecular analysis in shorter time and with lower reagent consumption than a standard laboratory. Their miniaturization interferes with the multiple functions that the biochemical procedures require. In order to address this issue, our paper presents, for the first time, the integration on a single glass substrate of different thin film technologies in order to develop a multifunctional platform suitable for on-chip thermal treatments and on-chip detection of biomolecules.