plant innate immunity

FISVE (Fisiologia Vegetale)

FISVE (Fisiologia Vegetale)

Plant cell walls are the first line of defense against pathogen attack and regulate growth under physiological and stress conditions. Plant cells constantly monitor wall integrity to adjust growth and modulate defenses. We have shown that plants with altered pectin composition constitutively express defense responses and are more resistant to infections, but are severely impaired in growth. 

Host Cell Wall Damage during Pathogen Infection: Mechanisms of Perception and Role in Plant-Pathogen Interactions.

The plant cell wall (CW) is a complex structure that acts as a mechanical barrier, restricting
the access to most microbes. Phytopathogenic microorganisms can deploy an arsenal of CWdegrading
enzymes (CWDEs) that are required for virulence. In turn, plants have evolved proteins
able to inhibit the activity of specific microbial CWDEs, reducing CW damage and favoring the
accumulation of CW-derived fragments that act as damage-associated molecular patterns (DAMPs)
and trigger an immune response in the host. CW-derived DAMPs might be a component of the

An EFR-Cf-9 chimera confers enhanced resistance to bacterial pathogens by SOBIR1- and BAK1-dependent recognition of elf18

The transfer of well-studied native and chimeric pattern recognition receptors (PRRs) to susceptible plants is a proven strategy to improve host resistance. In most cases, the ectodomain determines PRR recognition specificity, while the endodomain determines the intensity of the immune response. Here we report the generation and characterization of the chimeric receptor EFR-Cf-9, which carries the ectodomain of the Arabidopsis thaliana EF-Tu receptor (EFR) and the endodomain of the tomato Cf-9 resistance protein.

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