Integrated 3D microfluidic device for impedance spectroscopy in lab-on-chip systems
In this paper we demonstrate the implementation of a micro-scaled integrated system with the aim to sort, estimate and monitor the biomass of living cancer cells suspended in a culture medium. For this purpose, a 3D microfluidic network is designed to route small volumes of biological samples to the testing sites and dielectric spectroscopy is chosen as investigation method. Comparative electrical analyses are guaranteed by the separation of sole medium and medium-cells mixture in two different areas of the chip.