problematic severe asthma

The Severe Paediatric Asthma Collaborative in Europe (SPACE) ERS clinical research collaboration: enhancing participation of children with asthma in therapeutic trials of new biologics and receptor blockers

Asthma is one of the most common chronic diseases of childhood. Fortunately, most children with asthma have a mild or moderate form of the disease [1], and symptom control can be achieved by ensuring adequate provision of care and continuously addressing the basics in asthma management through shared decision-making with patients and their families. However, asthma remains difficult to treat for a small proportion of children who may be symptomatic despite aggressive maintenance therapy and after management issues like adherence to treatment have been addressed [2, 3].

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