Ricerc@Sapienza

Advancements in technologies employed in high-throughput next-generation sequencing
(NGS) methods are supporting the spread of studies that, combined with advances in computational
biology and bioinformatics, have greatly accelerated discoveries within basic and biomedical research
for many parasitic diseases. Here, we review the most updated “omic” studies performed on anisakid
nematodes, a family of marine parasites that are causative agents of the fish-borne zoonosis known as

The manufacturing processes of commercial probiotic strains may be affected in different ways in the attempt to optimize yield, costs, functionality, or stability, influencing gene expression, protein patterns, or metabolic output. Aim of this work was to compare different samples of a high concentration (450 billion bacteria) multispecies (8 strains) formulation produced at two different manufacturing sites, USA (US) and Italy (IT), by applying a combination of functional proteomics, metabolomics, and in vivo analyses.