Ricerc@Sapienza

Among painful disorders, migraine is distinguishable by its chronic pathology and episodic clinical manifestation. Only a small percentage of patients with migraine progress to a chronic form of migraine. Both peripheral and central portions of the trigeminal system are involved in the pathophysiology of migraine pain, as they are involved in the processes of peripheral and central sensitization, alongside various subcortical and cortical brain structures. This review focuses on clinical, neurophysiological, and neuroimaging data underscoring cortical pain processing in migraine.

Intercostobrachial neuropathy, often resulting in neuropathic pain, is a common complication of breast cancer surgery. In
this 1-year longitudinal study, we aimed at seeking information on the frequency, clinical features, and course of painless
and painful intercostobrachial neuropathy. We enrolled 40 women previously undergoing breast cancer surgery. In these
patients, we collected, at 3, 6 and 12 months after surgery, clinical and quantitative sensory testing (QST) variables to