Ricerc@Sapienza

Purpose: to investigate clinical outcomes in patients with large brain metastases from non-small-cell lung cancer (NSCLC) who received surgical resection and postoperative stereotactic radiosurgery or SRS alone. Patients and Methods: Two hundred and twenty-two patients with 241 large brain metastases (2–4 cm in size) who received surgery and multi-fraction SRS (mfSRS) to the resection cavity or mfSRS alone were analyzed. For all lesions the delivered dose was 3 x 9 Gy over three consecutive days. Primary endpoint of the study was local control (LC).

A feasibility study concerning the application of Poly-Allyl-Diglycol Carbonate (CR-39TM) solid state tracks detectors for fast survey of residual alpha contamination has been carried out at Casaccia Research Center, as a joint effort from ENEA, Sogin, and Sapienza University of Rome. The main target of the ac- tivity is to develop and set up a fast and economic method for assessing the presence of residual ura- nium, plutonium, and/or mixed oxides (MOX) traces on walls, floor, furniture, and small objects (PC- displays, keyboards, tools, etc.) of hot laboratories under decommissioning.

Generation of a well-aligned bunch train is of vital importance for preserving the beam quality in a
plasma wake-field accelerator. The simultaneous measurements of the relative misalignments in both
planes, of the individual femtosecond electron bunches with THz repetition rate in a train, are reported and
analyzed with simulations. The new method proposed in this paper demonstrates that the measurements can
be done quickly by applying a single quadrupole scan together with a radio-frequency deflector (RFD),

In this paper, the recently developed artificial material single layer (AMSL) method is applied to model a conductive shield for wireless power transfer (WPT) systems. This method is very efficient in the simulation of a complex setup, such as that occurring in the analysis of the magnetic field produced by a WPT system installed in an electrical vehicle (EV). In this application, a critical issue is the efficient and accurate modeling of conductive shields to evaluate the near field magnetic field.

This paper deals with the extension of the artificial material single-layer (AMSL) method, recently developed to model electromagnetically a thin conductive material using the finite-element method (FEM), to the more general case of transversally anisotropic shields. The analogy between the field equations and the multiconductor transmission line (MTL) equations is here used to calculate the admittance matrix of a thin anisotropic material. This admittance matrix is then imposed to be that of an equivalent circuit with lumped parameters.

A new artificial material single layer (AMSL) model is presented to solve shielding problem. The field penetration through the conductive shield is described by lossy transmission line equations. The resulting equations are used to numerically synthetize an equivalent material for the shield region having the same geometrical configuration of the original shield, but different specific constants.

In high voltage transmission lines, shield wires are periodically grounded and can be periodically sectionalized for several purposes. These two practices have important effects on multiconductor transmission lines, since both affect the wave propagation along the line. In this work, the attention is focused on the frequency behavior of the characteristic impedance. Moreover, the effect of wires transposition on the characteristic impedance is also investigated.

Deep underground laboratories (DULs) were originally created to host particle, astroparticle or nuclear physics experiments requiring a low-background environment with vastly reduced levels of cosmic-ray particle interference. More recently, the range of science projects requiring an underground experiment site has greatly expanded, thus leading to the recognition of DULs as truly multidisciplinary science sites that host important studies in several fields, including geology, geophysics, climate and environmental sciences, technology/instrumentation development and biology.

Cells, tissues and organs of astronauts aboard the International Space Station (ISS) are exposed to the damaging effects of microgravity and cosmic radiation. Space Agencies are forced to find effective therapeutic countermeasures to safeguard astronauts’ health. Since retina is one of the most vulnerable target, we undertook a project entitled The Coenzyme Q10 (CoQ10) as countermeasure for retinal damage onboard the International Space Station: the CORM project, funded by the Italian Space Agency (ASI) and launched in the summer 2017.

Electroporation of Jurkat T-lymphoma human cells was investigated using 10-MHz continuous waves and benchmarked against that at 100 kHz. Both cell poration and cell death were simultaneously monitored by fluorescence microscopy, and found to occur under approximately four times higher voltages at 10 MHz than that at 100 kHz. This weaker-than-expected increase in poration threshold could be explained by detailed analysis of the distributed effect often ignored in electroporation studies.