Feasibility of beta-particle radioguided surgery for a variety of “nuclear medicine” radionuclides
Purpose Beta-particle radioguided tumor resection may potentially overcome the limitations of conventional gamma-ray guided surgery by eliminating, or at least minimizing, the confounding effect of counts contributed by activity in adjacent normal tissues. The current study evaluates the clinical feasibility of this approach for a variety of radionuclides. Nowadays, the only ?- radioisotope suited to radioguided surgery is 90Y. Here, we study the ?- probe prototype capability to different radionuclides chosen among those used in nuclear medicine.