Ricerc@Sapienza

The district of San Lorenzo in Rome, so called because of its proximity to the basilica of
the same name, has a historical fabric and particular morphological and environmental
characteristics. Built on farmland belonging to the bourgeoisie at the end of the 1800s,
it attracted migrants who saw a certainty of work in the thriving construction sector. This
created the need to build cheap high-density dwellings for the working class, craftsmen
and the people, taking advan¬tage of the absence, until 1887, of a city building regula-

Skeletal muscle exhibits a high regenerative capacity, mainly due to the ability of satellite cells to replicate and differentiate in response to appropriate stimuli. Epigenetic control is effective at different stages of this process. It has been shown that the chromatin-remodeling factor HDAC4 is able to regulate satellite cell proliferation and commitment. However, its molecular targets are still uncovered.

Even though they have been considered out of fashion for years in the mainstream public debate, research practices and urban policies, the peripheries of the big cities are still a problem in Italy. Due to the economic crises and its effects at the urban scale, especially in terms of urban poverty and social exclusion, the problems of these areas are clearly increased without appropriate tools.

Morphogenetic events that occur during development and regeneration are energy demanding processes requiring profound rearrangements in cell architecture, which need to be coordinated in timely fashion with other cellular activities, such as proliferation, migration and differentiation. In the last 15 years, it has become evident that autophagy, an evolutionarily-conserved catabolic process that mediates the lysosomal turnover of organelles and macromolecules, is an essential " tool" to ensure remodelling events that occur at cellular and tissue levels.

Illustrazione del progetto per la riqualificazione delle parti comuni del complesso del Corviale.

The G124 project, the working group created by Renzo Piano, the senator of the Italian Republic, had as its objective the recovery of abandoned areas of the suburbs through small mending interventions that could trigger regeneration through new jobs, micro enterprises and start up, light construction sites and widespread. In particular, our research focuses on the project in Rome, Under the Viaduct of Presidents, in the north-east periphery, on the boundary of the city and discuss about the outcome as a product incubator in the territory.

The theme of minimal places, urban inserts that are discharged in appearance, forgotten in daily use, has been investigated at ecosystem

Revamping abandoned railways is often associated with leisure functions and non-routine trips. When areas evolve from rural settlements to conurbations with mixed land use and high travel demand, the reuse of no-longer-operational rail services can prove to be appropriate to meet such new requirements. This is the case of an abandoned railway in central Italy, the Sangritana Line, whose rehabilitation could serve a former rural area, now under continuous development.