Ricerc@Sapienza

Objectives: To investigate the long-term safety and efficacy of a treatment switch to dual ART with atazanavir/ ritonavir ! lamivudine versus continuing a standard regimen with atazanavir/ritonavir ! 2NRTI in virologically suppressed patients.

Aims: Although loop diuretics are the most commonly used drugs in acute heart failure (AHF) treatment, their short-term and long-term effects are relatively unknown. The significance of worsening renal function occurrence during intravenous treatment is not clear enough. This trial aims to clarify all these features and contemplate whether continuous infusion is better than an intermittent strategy in terms of decongestion efficacy, diuretic efficiency, renal function, and long-term prognosis.

Objectives: To describe our surgical technique and to report perioperative, 3-year oncological and functional outcomes of a single-center series of purely off-clamp robotic partial nephrectomy. Methods: A prospective renal cancer institutional database was queried, and data of consecutive patients treated with purely off-clamp robotic partial nephrectomy between 2010 and 2015 in a high-volume center were collected. Perioperative complications, and 3-year oncological and functional outcomes were assessed.

Introduction: Aim of the study was to compare perioperative, functional and oncological outcomes after off-clamp vs on-clamp robotic partial nephrectomy (RPN).

The aim of the present study was to find out if in children ablation of 50% of renal mass may be associated with a progressive renal damage (Brenner’s hypothesis). We collected 1035 adult or adolescent survivors who underwent nephrectomy for unilateral oncological or non-oncological causes during childhood. Stratification of all survivors for age revealed that the number of subjects with blood hypertension and/or renal dysfunction (glomerular filtration rate < 90 mL/min per 1.73 m2) to be significantly higher in survivors ≥30 years old in comparison with younger patients.

Introduction Children with unilateral renal tumor (URT) and preoperative renal
dysfunction (PRD) may benefit from nephron-sparing surgery (NSS). To test this
hypothesis, we studied the outcome of baseline renal function after nephrectomy or
NSS among children with URT.
Materials and Methods Retrospective records review of children with URT who
underwent nephrectomy (25 children) or NSS (11 children) at our institution. We
analyzed the estimated glomerular filtration rate (eGFR) changes over time among

Very low-calorie ketogenic diets (VLCKD) are an effective and increasingly used tool for weight loss. Traditionally considered high protein, ketogenic diets are often looked at with concern by clinicians due to the potential harm they pose to kidney function. We herein evaluated the efficacy and safety of a VLCKD in patients with obesity and mild kidney failure. A prospective observational real-life study was conducted on ninety-two patients following a VLCKD for approximately 3 months.