Ricerc@Sapienza

In recent years, several works have proved the reliability of the application of 3D modeling and spatial analysis in the study of stone tool use. Monitoring surface morphometry resulting from the use of lithic tools has the potential to objectively quantify and identify patterns of modifications associated to specific activities and worked materials.

Chopping tools/choppers provide one of the earliest and most persistent examples of stone tools produced and used by early humans. These artifacts appeared for the first time ~2.5 million years ago in Africa and are characteristic of the Oldowan and Acheulean cultural complexes throughout the Old World. Chopping tools were manufactured and used by early humans for more than two million years regardless of differences in geography, climate, resource availability, or major transformations in human cultural and biological evolution.

The aim of the present work is the development of a fast and reliable analytical multiresidue method for the confirmation of non-steroidal anti-inflammatory drugs residues in muscle, plasma and milk. The samples are extracted with organic solvent and purified with liquid-liquid extraction (LLE). The purified extract was analyzed by LC-HRMS.