Ricerc@Sapienza

This volume has its origin in a similarly entitled session organised at the 24th Annual Meeting of the European
Association of Archaeologists in Barcelona in 2018. The specific aim of both the session and this volume was
to measure acceptance of, and resistance to, outside influences within Mediterranean coastal settlements
and their immediate hinterlands, with an open time range, but with a particular focus on the processes not
reflecting simple commercial routes, but taking place at an intercultural level, in situations of developed

Animals respond to chemical stress with an array of gene families and pathways termed “chemical defensome”. In arthropods, despite many defensome genes have been detected, how their activation is arranged during toxic exposure remains poorly understood. Here, we sequenced the transcriptome of Anopheles stephensi larvae exposed for six, 24 and 48?hours to the LD50 dose of the insecticide permethrin to monitor transcriptional changes of defensome genes across time.