Saliva

The alteration of stress-related physiological parameters after probiotics administration in oral surgeons with different degrees of surgical experience

Purpose. Stress is a multifactorial and complex pathway, gaining growing attention from the healthcare community. Surgeons arc subjected to higher levels of stress, due to surgical procedures that arc demanding and repetitive; unfortunately, high-stress levels may also cause side-effects, as surgical mistakes. This study aimed to evaluate the efficacy of specific probiotics strains formula on stress levels in oral and maxillofacial surgeons, to improve their quality of life. Methods.

The treatment of black stain associated with of iron metabolism disorders with lactoferrin: a litterature search and two case studies

Among the various pathologies of the oral cavity, the formation of "unsightly black spots" on the surface of the tooth, universally known as Black Stain (BS) has recently been acquiring more interest. Usually BS is typically found in individuals in prepubertal age, even though it has been identified in adults associated with microbial exchange and / or with iron metabolism disorders. Microbial exchange concerns the possible exchange of bacteria between family members which can take place directly, through effusions, or indirectly, through brushes, cutlery or glasses.

Antiviral activity of reagents in mouth rinses against SARS-CoV-2

The oral cavity, an essential part of the upper aerodigestive tract, is believed to play an important role in the pathogenicity and transmission of SARS-CoV-2. The identification of targeted antiviral mouth rinses to reduce salivary viral load would contribute to reducing the COVID-19 pandemic. While awaiting the results of significant clinical studies, which to date do not exist, the commercial availability of mouth rinses leads us to search among them for reagents that would have specific antiviral properties with respect to SARS-CoV-2.

Lactobacillus brevis CD2 for Prevention of Oral Mucositis in Patients with Head and Neck Tumors. A multicentric randomized study

Background: Oropharyngeal mucositis occurs in virtually all patients with head and neck cancer receiving radiochemotherapy. The manipulation of the oral cavity microbiota represents an intriguing and challenging target. Patients and Methods: A total of 75 patients were enrolled to receive Lactobacillus brevis CD2 lozenges or oral care regimen with sodium bicarbonate mouthwashes. The primary endpoint was the incidence of grade 3 or 4 oropharyngeal mucositis during radiotherapy treatment.

Salivary alpha-synuclein in the diagnosis of parkinson's disease and progressive supranuclear palsy

Introduction: Alpha-synuclein (α-syn) aggregation is the pathological hallmark of Parkinson's Disease (PD). In this study, we measured α-syn total (α-syn total ), oligomeric α-syn (α-syn olig ) and α-syn olig /α-syn total ratio in the saliva of patients affected by PD and in age and sex-matched healthy subjects. We also compared salivary α-syn total measured in PD with those detected in Progressive Supranuclear Palsy (PSP), in order to assess whether salivary α-syn can be used as a biomarker for PD and for the differential diagnosis between PD and PSP.

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