Ricerc@Sapienza

Zbyněk Havlíček, poet and psychologist, wrote his first verses during the Second World War, when he joined a Prague surrealist group. The paper deals with Zbyněk Havlíček’s poem I live my life and write a poem (1961) and his poetics of poetry as an antagonist to the schizophrenia of totalitarian society; Prague is the stage on which the poet’s oniric and lucid walk occurs.

RIASSUNTO. Background. Il presente lavoro si propone di approfondire l’efficacia della Terapia Neurocognitiva Integrata (INT) secondo
il modello di Roder in un gruppo di schizofrenici cronici in condizione di residenzialità a lungo termine. Questo tipo di trattamento appare
particolarmente interessante perché, nell’ottica dei più recenti studi relativi alla schizofrenia come disturbo del neurosviluppo, permette di
agire sulle aree neuro- e socio-cognitive, che sono quelle maggiormente deteriorate. In più, il programma INT prevede l’uso di attività assistite

Several studies have reported motor symptoms in schizophrenia (SCZ), in some cases describing asymmetries in their manifestation. To date, biases were mainly reported for sequential movements, and the hypothesis was raised of a dopamine-related hemispheric imbalance. Aim of this research is to better characterize asymmetries in movement initiation in SCZ by exploring single actions. Fourteen SCZ patients and fourteen healthy subjects were recruited. On a trial-by-trial basis, participants were instructed to reach for one of eight possible targets.

Abstract not required.

The dopamine D2 and D3 receptors are implicated in schizophrenia and its pharmacological treatments. These receptors undergo intracellular trafficking processes that are modulated by dysbindin-1 (Dys). Indeed, Dys variants alter cognitive responses to antipsychotic drugs through D2-mediated mechanisms. However, the mechanism by which Dys might selectively interfere with the D3 receptor subtype is unknown. Here, we revealed an interaction between functional genetic variants altering Dys and D3.

The ?7 nicotinic receptor consists of identical subunits and is one of the most abundant acetylcholine receptor in the mammalian central nervous system. However its expression is also found in the peripheral nervous system as well as in the immune system and various peripheral tissues. It is involved in the regulation of several activities ranging from excitatory neurotransmission and the modulation of the release of several neurotransmitters, regulation of neurite outgrowth, and even neuronal survival/death.

The nerve growth factor (NGF) belongs to a family of proteins termed neurotrophins, consisting of NGF, brain-derived neuro- trophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5 and NT-6. Today, NGF is well recognized to mediate a large number of trophobiological actions resulting in neurotrophic, immunotrophic and/or metabotrophic effects. The pathobiology of neurode- generative diseases, including Alzheimer disease, psychiatric disorders (e.g.

Visceral aneurysms are rare entities, with a reported incidence of 0.01-2%. Fibromuscular dysplasia is a non-atherosclerotic, non-inflammatory artery disease which may predispose to aneurysmal degeneration. Schizophrenia has been linked to an increased cardiovascular risk because of the influence of traditional and disease specific risk factors. We report the case of a 44-year old male schizophrenic patient presenting with a ruptured giant aneurysm of superior mesenteric artery, managed by mesenteric ligation. The histologic diagnosis was fibromuscular dysplasia.