3D Tissue Modelling of Skeletal Muscle Tissue
Skeletal muscle tissue exhibits endogenous ability to regenerate. However, the self-repair mechanism is restricted only to small damages. The increasing number of extensive injuries of skeletal muscles due to various accidents, more active life-style or cancer resection, combined with the shortcomings of the conventional treatment procedures, creates demand for new, more advanced solutions. Muscle tissue engineering (TE) appears as a promising strategy for fabrication of tissue substitutes from biomaterials, cells and bioactive factors, alone or combined.