Ricerc@Sapienza

Management of a rare case of squamous cell carcinoma of the tongue in a patient affected by
progeria.

In this study six patients with oral carcinoma were subsequently subjected to surgery. Following surgical operation, patients highlight functional and psychosocial problems such as dysphagia, dysarthria and difficulties in everyday life. These issues are much greater as the tongue is affected by the tumor. The removal of part or all of the tongue, generally associated to teeth loss, is related to the severity of functional problems for the patient such as chewing, phoning and swallowing.

Cleft lip and cleft palate (CP) are the most common facial malformations. Two-dimensional (2D) ultrasound (US) is the first-line examination in the prenatal diagnosis of CP. Three-dimensional, four-dimensional US and MRI provide a better detection of facial clefts. We present two fetuses with micrognathia and suspected secondary CP on 2D US: fetal tongue appeared in an unusual position (low tip and high dorsum position) and showed uncoordinated movements. MRI did not confirm the US suspicion, but at birth the two fetuses were affected by Pierre Robin sequence.

Lingual cyst with respiratory epithelium (LCRE) is a very rare congenital cyst of the tongue, floor of the mouth, pharynx or hypopharynx with 21 cases reported in the literature (1, 2). Differential diagnosis is very important for patients presenting with lingual cysts, as this may impact treatment and follow-up. LCRE should be included in the different diagnosis of dermoid cyst (3), teratoid cyst (4), epidermoid cyst (5), thyroglossal duct cyst (6), lymphoepithelial cyst (7), mucocele or ranula (8).