Ricerc@Sapienza

The increasing interest for obtaining pure, single enantiomers of chiral organic compounds has greatly expanded the progress of new synthetic procedures, especially in the field of chiral drugs, agrochemicals, flavors, and natural products. A parallel trend has been observed in the development of stereoselective separation methods for the precise and accurate measurements of the enantiomeric purity of chiral compounds.

The ever-increasing need for enantiomerically pure chiral compounds has greatly expanded the number of enantioselective separation methods available for the precise and accurate measurements of the enantiomeric purity. The introduction of chiral stationary phases for liquid chromatography in the last decades has revolutionized the routine methods to determine enantiomeric purity of chiral drugs, agrochemicals, fragrances, and in general of organic and organometallic compounds.