The utility of in vitro metabolism studies coupled to liquid chromatography-tandem mass spectrometry for the selection of diagnostic markers of novel psychoactive substances: the case of 4,4’-DMAR
para-Methyl-4-methylaminorex (4,4’-DMAR) is a synthetic, substituted oxazoline derivative and analogue of the scheduled aminorex and 4-methylaminorex (4-MAR), both of which originally designed and synthesized as appetite suppressants. The psychostimulant properties of these substances are due to the interaction with dopamine transporter (DAT), serotonin transporter (SERT) and norepinephrine transporter (NET).