LOW DISCRIMINATION POWER OF THE YFILER™ PLUS PCR AMPLIFICATION KIT IN AFRICAN POPULATIONS. DO WE NEED MORE RM Y-STRs?
Recently, thirteen rapidly mutating Y-STRs (RM Y-STRs), characterized by a mutation rate higher than 10−2/STR/generation, have been proven to be extremely useful in distinguishing among close male relatives. Six of these RM-YSTRs have been included in the Yfiler™ Plus PCR Amplification Kit, which shows the highest discriminatory power among Y-STR commercial multiplex currently available. In this study, we used Yfiler Plus to analyze 1437 males from eastern, northern and sub-Saharan Africa (462, 477 and 498 subjects, respectively).